Release date: 2009-03-30 The study, led by researchers from the National Institute on Alcohol Abuse and Alcoholism and the Japan Jiulibin Alcohol Research Center, found that approximately one-third of East Asians lack a functional form of the enzyme aldehyde dehydrogenase 2 (ALDH2). This enzyme plays a crucial role in breaking down acetaldehyde, a toxic byproduct of alcohol metabolism. When ALDH2 is missing or not working properly, acetaldehyde accumulates in the body, leading to the characteristic "flushing" reaction—redness in the face and neck—after even small amounts of alcohol consumption. According to the researchers, individuals with this genetic deficiency face a much greater risk of esophageal cancer as their alcohol intake increases. The study showed that people who blush easily when drinking, especially red wine, have a far higher chance of developing the disease compared to those who do not show such reactions. Moreover, even with comprehensive treatment, patients who develop esophageal cancer due to this condition have a very low survival rate, with only 12% to 31% surviving more than five years. This finding underscores the importance of understanding individual genetic differences when it comes to alcohol metabolism and cancer risk. It also highlights the need for increased awareness among East Asian populations about the dangers of alcohol consumption, especially for those who experience facial flushing. Health professionals recommend that individuals with this genetic trait should consider limiting or avoiding alcohol altogether to reduce their risk of serious health complications. Blend Garlic,Blend Garlic and Onion,Garlic Salt,Garlic pizza Henan Sunny Foodstuff Co.,Ltd. , https://www.hnsunnyfood.com
A recent study published in the journal *PLOS Medicine* has revealed that East Asians, particularly those who experience facial flushing after drinking alcohol, are at a significantly higher risk of developing esophageal cancer. The research, conducted by scientists from the United States and Japan, highlights a genetic factor that may explain this increased vulnerability.
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East Asians who drink blush are prone to esophageal cancer
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