The United States invented new technology to induce cells to grow into artificial blood vessels

The United States invented new technology to induce cells to grow into artificial blood vessels

Release date: 2007-12-25

In a groundbreaking development, scientists from the Massachusetts Institute of Technology have created a novel technology that encourages cells to form parallel tube-like structures, potentially acting as artificial blood vessels in the future. This innovative method was recently published in the journal *Advanced Materials*.

The research opens up new possibilities for building nanosystems used in tissue engineering. The focus of the study was on vascular tissue—essential components of the circulatory system, including capillaries and microvessels. To achieve this, the team developed a specialized surface that acts as a template for growing capillary-like structures. Using advanced microfabrication tools from the Draper Laboratory in Cambridge, they designed templates that can guide cell growth at the nanoscale. These surfaces are patterned with ridges and grooves that direct how cells align and develop.

In the future, these artificially engineered blood vessels could be implanted into organs such as the kidneys, liver, or heart, where large amounts of vascular tissue are needed to transport nutrients, oxygen, and waste products. Researchers believe that this approach is particularly effective when using endothelial progenitor cells (EPCs), which are more mature and better suited for forming stable structures. Previous attempts with other cell types failed to produce similar results.

By culturing tissues on patterned surfaces, scientists gain greater control over the formation of vascular networks. In a further step, the team successfully transplanted lab-grown capillaries into living animals, aiming to integrate them with the host’s natural tissues. This research represents a significant leap forward in regenerative medicine and could one day revolutionize organ transplantation and tissue repair. ——Shanghai Medical Device Industry Association

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