Oral anti-cancer drugs can greatly reduce the efficacy when used together with other drugs

Oral anti-cancer drugs can greatly reduce the efficacy when used together with other drugs

US researchers recently discovered that many oral anti-cancer drugs, when used in combination with other drugs, have a drastically reduced efficacy and may even produce side effects.

The researchers found that 23% to 74% of the patients who used 9 oral anticancer drugs, respectively, were not able to cause the anticancer drug to fail due to taking other drugs at the same time. The nine anticancer drugs listed by the researchers are kinase inhibitors, including: Imatinib (Gleevec), Erlotinib (Tarcaine), Prasae, Everolimus, Lapati Nilotinib, pazopanib, sorafenib and sunitinib. Drugs that may affect the efficacy of these anticancer drugs include some antibiotics and antifungal drugs.

However, Dr. Steinick of the US Research Institute pointed out that in practical applications, oncologists are not necessarily aware of prescriptions prescribed by other doctors for patients, which poses a potential hazard to those who use oral drugs to treat cancer, because Complex drug use increases the chance of interaction between drugs.

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