Easy to operate drug dryer

Abstract: In view of the current structural pollution of equipment for small-scale pharmaceutical refining and drying, the tray-type drying operation is backward, the product yield is low, especially the harm of highly toxic drugs to the environment and operators, and a small vacuum medicine with simplified structure and easy operation is introduced. Dryer.
Key words: no seal, inclined uniaxial support, low temperature saturated steam
1 Overview In the pharmaceutical refining equipment, the rotary vacuum dryer is a kind of equipment with relatively complicated structure and high processing requirements. The first is to ensure that the degree of vacuum must be set with a rotating mechanical seal. The chemicals in the rotary dynamic drying are easy to dust, and in order to reduce product loss, the dust must be prevented from being lost with the vacuum exhaust. Since the water vapor in the vacuum drying is saturated, it is condensed and precipitated slightly below the dew point, and is condensed on the wall together with the product dust, so it is necessary to set the exhaust gas filter inside the dryer. It is also necessary to provide reliable heat to the equipment in the rotary motion and to detect the temperature of the control product and the heat source. All of the structures need to strictly comply with the GMP specifications, thus complicating the structure of the rotary vacuum dryer.
The equipment needs to be divided into large and small ones according to the scale. The large dryer barrel has large space inside, easy to process welding, cleaning and maintenance, but the space inside the small dryer is very narrow. The conventional small double cone vacuum dryer cylinder can no longer be added to the exhaust gas filtration. The cyclone separator can only be used in the low-efficiency cyclone separator, which causes the saturated steam to agglomerate in the outer tube line and the cyclone separator together with the emitted product dust, making it difficult for many products with high added value. Recycling. Because some pharmaceutical refining treatments are small, such as a 50-liter dryer, if still using the same structure as 5000 liters, not only increases the cost of equipment, but also adds cumbersome. Therefore, a small-sized pharmaceutical refiner should not copy the structure of a large dryer, but it should not simplify the functional structure due to its small size, so as to avoid side effects such as yield.
2 Small vacuum drug dryer The structure of the small vacuum drug dryer is shown in the figure (50 liters).
2.1 Structure Introduction The specifications of the small vacuum drug dryer are 50 liters, 100 liters, 200 liters and 300 liters. The basic structure of the unsealed asymmetric double cone vacuum dryer eliminates the structural pollution hazard caused by the vacuum seal. Because the cylinder is small and light, the oblique single-axis support is simple and easy to accept from the structural load-bearing or visual point of view. Although the rotating shaft of the cylinder is inclined, the low point of the outlet flange is still low through the cylinder. level. The filter is arranged at the rotation center of one end of the cylinder body, and the exhaust gas is connected to the vacuum suction pipe at the center of the rotating shaft through the bottom center of the cylinder body, and then is extracted by the rotary vacuum joint, and the organic pipe can be recycled on the extracted vacuum pipe. A solvent condenser that recovers various organic solvents to reduce atmospheric pollution. There is only one inlet and outlet (cleaning hole), and the semi-circular evaporating heating coil of the jacket is ≤0.1MPa. The saturated steam is connected to the outer heating coil of the jacket through the steam rotary joint and the connecting pipe in the rotating shaft. The outer jacket also serves as a low-temperature steam generator to produce low-temperature saturated steam of 25-100 ° C for drying and heating. Therefore, this machine does not have a hot water circulation system for drying, which makes the whole machine compact and easy to manage.
2.2 Performance The small vacuum drug dryer has a much higher F(m2)/V(m3) value than the large one, so the drying speed is very fast. Because the dryer uses a low temperature saturated steam (25-100 °C) heat source, it can be used. Loose, including various highly heat sensitive biological products, undergo rapid low temperature drying of <20. It is also suitable for all kinds of loose and highly toxic or highly toxic drugs with strict GMP requirements. For example, the use of special discharge cylinders can achieve a large product yield and reduce environmental pollution.
The dryer does not have the same rotary vacuum seal as the conventional double cone vacuum dryer, and there is no possibility of mechanical wear and foreign matter contamination. The drying temperature of the dryer is controlled by the amount of primary steam to stabilize the secondary low-temperature steam drying temperature, and the secondary drying temperature is set to determine the high operating temperature of the dried zui. Even if the product has been dehydrated, the product can be ensured that the product does not exceed the drying temperature value. . The dryer has no structural pollution, fast drying speed, short natural retention time, and is heated by stable and efficient low-temperature steam, so it can achieve high drying efficiency and high product quality.
The dryer extracts the exhaust without product dust, and the product yield is ≥ 99%.
The dryer can be fed and unloaded at one time, and the unloading is clean and neat, and can be equipped with a special clamp type drying cylinder. The filter is easy to fold and unload. After the filter is taken out, the cylinder is easy to clean, so the operation is very easy.
3 Economical In addition to high efficiency, high quality and high yield, this dryer is highly simplistic in structure and reasonable in designing materials. All of this is to get rid of the old and backward drying equipment as soon as the production of small-scale pharmaceuticals, biological products and fine chemical products. For all kinds of medicines with high value, Zui is important for high quality and high yield. For all kinds of highly toxic drugs, in addition to high quality and high yield, it is also necessary to ensure that the product dust is not leaked. To ensure that the environment is free from contamination and the safety of the operator is safe, this dryer can fully meet the above requirements. This dryer technology has been applied for a patent, patent No. 3.

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