Bp Pharmaceutical Cyproheptadine Hydrochloride for Anti-Allergic CAS 41354-29-4

Bp Pharmaceutical Cyproheptadine Hydrochloride for Anti-Allergic CAS 41354-29-4

  • Model NO.: 41354-29-4
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Synonym: Periactinolhydrochloride
  • MW: 323.86
  • Appearance: White Powder
  • Usage: Urticaria, Allergic
  • Lead Time: Within 24 Hours After We Get Your Payment
  • Transport Package: Discreet Package
  • Origin: China
  • Powder: Yes
  • Certification: HSE, ISO 9001
  • State: Solid
  • CAS: 41354-29-4
  • Mf: C21h22cln
  • Einecs: 213-535-1
  • Grade: Pharma Grade
  • MOQ: 10g
  • Trademark: Saichuang
  • Specification: Enterprise standard
BP Pharmaceutical Cyproheptadine Hydrochloride for Anti-Allergic CAS 41354-29-4


Quick Detail
Product Name
Cyproheptadine Hydrochloride
 
Synonym
Cyproheptadine HCL;Cyproheptadine Hydrochloride; Cyproheptadine Hydrochloride Hydrate;Cyproheptadine Hydrochloride Sesquihydrate;
 
CAS
41354-29-4
 
MF
C21H22ClN
 
MW
323.86
 
EINECS
213-535-1
 
Purity
99%
 
Appearance
White Powder
 
Standard
BP
 
Melting Point
165 °C (dec.)(lit.)
 
Usage
Urticaria, allergic and contact dermatitis, allergic asthma
 
MOQ
10g
 



Cyproheptadine hydrochloride Description:

Cyproheptadine hydrochloride is a kind of pipecolic antihistamines,it can compete with histamine released from the organization for H1 receptor on effector cells , thereby it can prevent the onset of an allergic reaction, and release histamine-induced spasm and congestion effects, this product has a strong H1 receptor antagonism, its anti-histamine effect is stronger than chlorpheniramine, promethazine . There are mild to moderate anti-serotonin effects and anticholinergic effects. In addition, there is a stimulate appetite effect, and weight gains after a certain time.


Cyproheptadine hydrochloride Application:

Clinically cyproheptadine hydrochloride is mainly used for acute and chronic urticaria (especially it has a good effect on cold urticaria), papular urticaria, angioedema, atopic eczema, contact dermatitis, food allergy, drug allergy, allergic rhinitis, hay fever, allergic conjunctivitis, allergic to insect stings and migraine.

It has some therapeutic effect on bronchial asthma. It is acceptable for the adjuvant treatment of Cushing's syndrome, acromegaly. In addition,as an appetite enhancer,it is used for neuropathic fear of food. There are reports about acanthosis nigricans treatment, prevention of necrotizing pyoderma.


Cyproheptadine hydrochloride COA:
Product name  
Cyproheptadine HCL
 
CAS No. 41354-29-4 Outer Packing  
 1KG/bag
 
Production date 2016.09.04  
Shelf life
 		  2019.09.03
Standard adopted  
USP32
 
Items of analysis Specification
Results
 
Appearance  
A white or slightly yellow,odorlessor practicallyodorless,crystalline powder.
 		 Complies
 
Identification		  
The IR spectrum of the preparation
of test
 		 Complies
 
Acidity(0.05% as HCL, ml)
 		 Not more than 0.15ml 0.13ml
 
Related substances
 		 Compliance Complies
 
Water		  
 
7.0%~9.0 %

 		  
 
8.2%
 
 
Residue On Ignition
 		 ≤0.1% 0.06%
 
Assay
 		  not less than 98.5% 99.61%
 
 Heavy Metals
 		 ≤0.002% Complies
Conclusion
Qualified
 


Cyproheptadine hydrochloride Medical Usage:

1. Cyproheptadine is used to treat allergic reactions (specifically hay fever). It is also used to treat vasomotor mucosal edema, including vasomotor rhinitis and edema of the throat.

2, It has shown effectiveness in the treatment of nightmares, including those related to post-traumatic stress disorder.

3. It has been used in the management of moderate to severe cases ofserotonin syndrome, a complex of symptoms associated with the use ofserotonergic drugs, such as selective serotonin reuptake inhibitorsand monoamine oxidase inhibitors), and in cases of high levels of serotonin in the blood resulting from a serotonin-producingcarcinoid tumor.

4. It can also be used as a preventive measure against migraine in children and adolescents. In Australia this is the only indication for which cyproheptadine is subsidised by the PBS.

5. It can relieve SSRI-induced sexual dysfunction and drug-inducedhyperhidrosis (excessive sweating).

6. It is also used in the treatment of cyclical vomiting syndrome.

7. Use of the drug can stimulate the appetite and may lead to weight gain, which is helpful for underweight people.

8. According to a small study, cyproheptadine hydrochloride has been found to improve sleep, calmness, and mood and energy levels, and to improve both negative and (sometimes even) positive psychotic symptoms in a subgroup of chronic schizophrenics who did not respond (either completely or sufficiently) to other therapies.

9. Cyproheptadine may improve akathisia in patients on antipsychotic medications.

10. In clinical trials in which cyproheptadine was used as an adjunct to antipsychotic treatment for patients with schizophrenia, an improvement in negative symptoms was seen.


Cyproheptadine hydrochloride Dosage:

(1) Allergic diseases: adult, once 2~4mg, one day 2 or 3 times.

(2) Cushing's syndrome, applicable to the treatment of cases of bilateral adrenal hyperplasia, it can inhibit the hypothalamic release of corticotropin releasing hormone (CRH) and inhibit the secretion of pituitary adrenocorticotropic hormone (ACTH), thereby lowering plasma ACTH and cortisol levels; adults start one day 8mg, which can be gradually increased to one day24mg; the usual dose is one day 12 ~ 24mg, divided doses,it needs long-term use; in the case of cortical function inadequate after total resection or subtotal bilateral adrenal, on one hand ,supple corticosteroids, on the other hand,take cyproheptadine,which can reduce the chance of occurrence of pituitary tumors.


Advantage:

1. Packaging & delivery. We do have professional team for package and shipment.Special & safe way to ship all the products to the destination country no matter the quantity or location. Fast and discreet shipment can be arranged for customs clearance guaranteed, security is the key& we do have reshipping policy.

2. Our advantages
We are back to introduce us to more clients again! Actually, we are in the business as a professional raw material lab supplier for over 15 years, we have more than enough experience to handle everything in the right way.

a. Our products did & do be shipped safely to many countries with mass quantity always.

b. We do get professional team, esp., for package & shipment, do have strong connection in shipping system, all the parcels are sent via traceable couriersas UPS, FedEx, DHL & so on, do offer customs clearance guaranteed to the destination country.

c. Products are in prompt stock, chargeable samples are available at any time,can be shipped out immediately upon the requirement.

d. You get the absolutely right choice if want the best stuff & service, high quality,good price, fast and safety delivery guaranteed, we do have reshipping policy once anyuncontrollable incident happe
 

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